Alogoneurodystrophy

Description

reflex sympathetic dystrophy: Complex regional pain syndrome type 1 (CRPS1) is a form of complex regional pain syndrome (see this term) in which the pain is disproportionate to any known inciting event and is characterized by continuous pain, allodynia, or hyperalgesia as well as edema, coloration (changes in skin blood flow), or abnormal sudomotor activity in the region of pain. Onset of CRPS1 symptoms may occur within a few days to a month after an injury or trauma to the affected limb.

Data source
FinnGen phenocode M13_ALGONEURO
Hospital Discharge registry ICD-10: M890
Cause of Death registry ICD-10: M890
Level in the ICD-hierarchy 4
First defined in version DF2
Ontology
DOID 1811
GWAS catalog 1001147
MESH D012019
SNOMED CT 50642008

Key figures

Sex All Female Male
Number of individuals 242 176 66
Unadjusted prevalence (%) 0.18 0.23 0.11
Mean age at first event (years) 48.81 47.86 51.37
Median number of events / individual 2 2 2

Clinical metrics

Sex All Female Male
Recurrence within 6 months (%) 56.2 57.39 53.03
Case fatality at 5-years (%) 1.65 1.7 1.52

Associations