Ankylosing spondylitis

Description

ankylosing spondylitis: An autoimmune chronic inflammatory disorder characterized by inflammation in the vertebral joints of the spine and sacroiliac joints. It predominantly affects young males. Patients present with stiffness and pain in the spine.

Data source
FinnGen phenocode M13_ANKYLOSPON
Hospital Discharge registry ICD-10: M45, ICD-8: 7124
Cause of Death registry ICD-10: M45, ICD-8: 7124
Level in the ICD-hierarchy 4
First defined in version DF2
Ontology
DOID 7147
GWAS catalog 0003898
MESH D013167
SNOMED CT 9631008

Key figures

Sex All Female Male
Number of individuals 819 387 432
Unadjusted prevalence (%) 0.62 0.52 0.75
Mean age at first event (years) 43.27 43.95 42.65
Median number of events / individual 4 4 5

Clinical metrics

Sex All Female Male
Recurrence within 6 months (%) 62.88 62.27 63.43
Case fatality at 5-years (%) 0.98 1.03 0.93

Event distributions

Associations