Radial styloid tenosynovitis [de Quervain]

Description

De Quervain disease: Stenosing tenosynovitis of the abductor pollicis longus and extensor pollicis brevis tendons in the first dorsal wrist compartment. The presenting symptoms are usually pain and tenderness at the radial styloid. The cause is almost always related to overuse injury or is associated with rheumatoid arthritis.

Data source
FinnGen phenocode M13_DEQUERVAIN
Hospital Discharge registry ICD-10: M654, ICD-9: 7270A
Cause of Death registry ICD-10: M654, ICD-9: 7270A
Level in the ICD-hierarchy 4
First defined in version DF2
Ontology
DOID 14107
GWAS catalog 1000891
MESH D053684
SNOMED CT 21794005

Key figures

Sex All Female Male
Number of individuals 466 368 98
Unadjusted prevalence (%) 0.35 0.49 0.17
Mean age at first event (years) 47.27 47.55 46.25
Median number of events / individual 1 1 1

Clinical metrics

Sex All Female Male
Recurrence within 6 months (%) 25.32 25.27 25.51
Case fatality at 5-years (%) 0.21 0.27 0.0

Associations