Rheumatoid arthritis


rheumatoid arthritis: A chronic, systemic autoimmune disorder characterized by inflammation in the synovial membranes and articular surfaces. It manifests primarily as a symmetric, erosive polyarthritis that spares the axial skeleton and is typically associated with the presence in the serum of rheumatoid factor.

Data source
FinnGen phenocode M13_RHEUMA
Hospital Discharge registry ICD-10: M05/M06, ICD-9: 7140B/7140A, ICD-8: 712[1-3]
Cause of Death registry ICD-10: M06/M05, ICD-9: 7140A/7140B, ICD-8: 712[1-3]
Level in the ICD-hierarchy 4
First defined in version DF2
DOID 7148
GWAS catalog 0000685
MESH D001172
SNOMED CT 69896004

Key figures

Sex All Female Male
Number of individuals 3638 2559 1079
Unadjusted prevalence (%) 2.74 3.41 1.88
Mean age at first event (years) 51.88 51.04 53.89
Median number of events / individual 7 7 6

Clinical metrics

Sex All Female Male
Recurrence within 6 months (%) 72.98 73.54 71.64
Case fatality at 5-years (%) 2.78 2.11 4.36