Systemic lupus erythematosus

Description

systemic lupus erythematosus: An autoimmune multi-organ disease typically associated with vasculopathy and autoantibody production. Most patients have antinuclear antibodies (ANA). The presence of anti-dsDNA or anti-Smith antibodies are highly-specific.

Data source
FinnGen phenocode M13_SLE
Hospital Discharge registry ICD-10: M32, ICD-8: 7431
Cause of Death registry ICD-10: M32, ICD-8: 7431
Level in the ICD-hierarchy 3
First defined in version DF2
Ontology
DOID 9074
GWAS catalog 0002690
MESH D008180
SNOMED CT 55464009

Key figures

Sex All Female Male
Number of individuals 299 250 49
Unadjusted prevalence (%) 0.23 0.33 0.09
Mean age at first event (years) 47.57 47.19 49.53
Median number of events / individual 5 7 3

Clinical metrics

Sex All Female Male
Recurrence within 6 months (%) 65.55 65.6 65.31
Case fatality at 5-years (%) 4.35 4.4 4.08

Associations