Other disorders of kidney and ureter

Description

renal osteodystrophy: Decalcification of bone or abnormal bone development due to chronic KIDNEY DISEASES, in which 1,25-DIHYDROXYVITAMIN D3 synthesis by the kidneys is impaired, leading to reduced negative feedback on PARATHYROID HORMONE. The resulting SECONDARY HYPERPARATHYROIDISM eventually leads to bone disorders.

Data source
FinnGen phenocode N14_KIDUROTH
Hospital Discharge registry ICD-10: N28/N29/N27/N26/N25
Cause of Death registry ICD-10: N28/N27/N26/N25/N29
Include N14_DISIMPAIRRENTUB, N14_UNSPECKIDCONTR, N14_SMALLKIDNEY, N14_CYSTKID, N14_OTHETNASKIDUR, N14_OTHKIDURINOTH
Level in the ICD-hierarchy 2
First defined in version DF2
Ontology
DOID 13068
GWAS catalog 1001152
MESH D012080
SNOMED CT 16726004

Key figures

Sex All Female Male
Number of individuals 904 476 428
Unadjusted prevalence (%) 0.68 0.63 0.75
Mean age at first event (years) 52.56 48.11 57.5
Median number of events / individual 1 1 1

Clinical metrics

Sex All Female Male
Recurrence within 6 months (%) 25.77 26.89 24.53
Case fatality at 5-years (%) 5.42 3.57 7.48

Associations