Placental disorders

Description

twin-to-twin transfusion syndrome: Twin twin transfusion syndrome (TTTS) is a rare condition seen in twin monochorionic pregnancies, typically developing during the 15-26 week gestation period and usually due to unbalanced intertwin placental anastomoses, where an unequal exchange of blood between twins causes oligohydramnios in one sac and polyhydramnios in the other which can lead to a high perinatal mortality rate and a high rate of disability in survivors if left untreated

Data source
FinnGen phenocode O15_PLAC_DISORD
Hospital Discharge registry ICD-10: O43
Cause of Death registry ICD-10: O43
Sex specific endpoint 2
Level in the ICD-hierarchy 3
First defined in version DF3
Ontology
DOID 13576
GWAS catalog 1001221
MESH D005330
SNOMED CT 13404009

Key figures

Sex All Female Male
Number of individuals 51 51 N/A
Unadjusted prevalence (%) 0.04 0.07 N/A
Mean age at first event (years) 31.98 31.98 N/A
Median number of events / individual 1 1 N/A

Clinical metrics

Sex All Female Male
Recurrence within 6 months (%) 3.92 3.92 N/A
Case fatality at 5-years (%) 0.0 0.0 N/A

Associations