Other (seronegative) rheumatoid arthritis, wide

Description

adult-onset Still's disease: adult-onset Still disease (AOSD) is a rare inflammatory multisystem disorder characterized clinically by fever of unknown origin, arthralgia or arthritis, hyperleucocytosis, and typical skin rash.

Data source
FinnGen phenocode RHEUMA_OTHER_WIDE
Hospital Discharge registry ICD-10: M06, ICD-9: 7140B
Cause of Death registry ICD-10: M06, ICD-9: 7140B
First defined in version DF2
Ontology
DOID 14256
GWAS catalog 0007135
MESH D016706
SNOMED CT 239920006, 68190001

Key figures

Sex All Female Male
Number of individuals 1701 1211 490
Unadjusted prevalence (%) 1.28 1.61 0.85
Mean age at first event (years) 54.94 54.13 56.95
Median number of events / individual 3 3 3

Clinical metrics

Sex All Female Male
Recurrence within 6 months (%) 57.14 58.71 53.27
Case fatality at 5-years (%) 4.53 3.72 6.53

Associations