Seropositive rheumatoid arthritis, wide

Description

Felty's syndrome: Felty syndrome (FS), also known as ''super rheumatoid'' disease, is a severe form of rheumatoid arthritis (RA), characterized by a triad of RA, splenomegaly and neutropenia, resulting in susceptibility to bacterial infections.

Data source
FinnGen phenocode RHEUMA_SEROPOS_WIDE
Hospital Discharge registry ICD-10: M05, ICD-9: 7140A
Cause of Death registry ICD-10: M05, ICD-9: 7140A
First defined in version DF3
Ontology
DOID 11042
GWAS catalog 0007269
MESH D005258
SNOMED CT 57160007

Key figures

Sex All Female Male
Number of individuals 2687 1918 769
Unadjusted prevalence (%) 2.03 2.55 1.34
Mean age at first event (years) 54.91 54.07 57.0
Median number of events / individual 7 7 6

Clinical metrics

Sex All Female Male
Recurrence within 6 months (%) 74.77 74.97 74.25
Case fatality at 5-years (%) 3.24 2.55 4.94

Associations