Systemic lupus erythematosus, unspecified

Description

systemic lupus erythematosus: An autoimmune multi-organ disease typically associated with vasculopathy and autoantibody production. Most patients have antinuclear antibodies (ANA). The presence of anti-dsDNA or anti-Smith antibodies are highly-specific.

Data source
FinnGen phenocode SLE_NOS
Hospital Discharge registry ICD-10: M329
Cause of Death registry ICD-10: M329
First defined in version DF2
Ontology
DOID 9074
GWAS catalog 0002690
MESH D008180
SNOMED CT 55464009

Key figures

Sex All Female Male
Number of individuals 244 209 35
Unadjusted prevalence (%) 0.18 0.28 0.06
Mean age at first event (years) 50.02 49.68 52.06
Median number of events / individual 6 6 4

Clinical metrics

Sex All Female Male
Recurrence within 6 months (%) 68.44 67.94 71.43
Case fatality at 5-years (%) 4.1 4.78 0.0

Associations