Other coagulation defects

Description

thrombophilia: A condition characterized by an abnormally high level of thrombi. Causes include thrombotic thrombocytopenic purpura, disseminated intravascular coagulation, bone marrow disorders, and antiphospholipid antibody syndrome.

Data source
FinnGen phenocode D3_COAGOTHER
Hospital Discharge registry ICD-10: D68
Cause of Death registry ICD-10: D68
Include D3_VONVILLEBRAND, D3_HEREDFXIDEF, D3_HEREDOTHCLOFACTORS, D3_HAEMORRHAGCIRGUANTICO, D3_ACQCOAFACDEF, D3_PRIMTHROMBOPHILIA, D3_OTHTHROMBOPHILIA, D3_COAGDEFNAS
Level in the ICD-hierarchy 3
First defined in version DF2
Ontology
DOID 2452
GWAS catalog 0009315
MESH D019851
SNOMED CT 234467004

Key figures

Sex All Female Male
Number of individuals 500 334 166
Unadjusted prevalence (%) 0.38 0.44 0.29
Mean age at first event (years) 49.59 46.09 56.64
Median number of events / individual 1 2 1

Clinical metrics

Sex All Female Male
Recurrence within 6 months (%) 35.8 41.92 23.49
Case fatality at 5-years (%) 14.0 8.08 25.9

Associations