Amyloidosis
Description
amyloidosis: A disorder characterized by the localized or diffuse accumulation of amyloid protein in various anatomic sites. It may be primary, due to clonal plasma cell proliferations; secondary, due to long standing infections, chronic inflammatory disorders, or malignancies; or familial. It may affect the nerves, skin, tongue, joints, heart, liver, spleen, kidneys and adrenal glands.
Data source
| FinnGen phenocode | E4_AMYLOIDOSIS |
| Hospital Discharge registry | ICD-10: E85 |
| Cause of Death registry | ICD-10: E85 |
| Include | E4_AMYL_NONNEURO, E4_AMYL_NEUROHER, E4_AMYL_HEREDOFAM, E4_AMYL_SCNDSYST, E4_AMYL_ORGAN, E4_AMYLNAS |
| Level in the ICD-hierarchy | 3 |
| First defined in version | DF2 |
Key figures
| Sex | All | Female | Male |
| Number of individuals | 136 | 80 | 56 |
| Unadjusted prevalence (%) | 0.1 | 0.11 | 0.1 |
| Mean age at first event (years) | 60.48 | 58.29 | 63.6 |
| Median number of events / individual | 3 | 4 | 2 |
Clinical metrics
| Sex | All | Female | Male |
| Recurrence within 6 months (%) | 56.62 | 58.75 | 53.57 |
| Case fatality at 5-years (%) | 24.26 | 22.5 | 26.79 |