Chrondropathies

Description

relapsing polychondritis: Relapsing polychondritis (RP) is a rare, clinically heterogeneous, multisystemic inflammatory disease characterized by inflammation of the cartilage and proteoglycan rich structures leading to cartilage damage with joint, ocular and cardiovascular involvement.

Data source
FinnGen phenocode M13_CHRONDROPATHIES
Hospital Discharge registry ICD-10: M91/M93/M94/M92
Cause of Death registry ICD-10: M93/M92/M91/M94
Include M13_JUVOSTEOCHONRHIP, M13_OSTEOCHONDROPATHY, M13_TIETZE, M13_RELAPSPOLYCHONDR, M13_CHONDROMALACIA, M13_CHONDROLYSIS
Level in the ICD-hierarchy 3
First defined in version DF2
Ontology
DOID 2556
GWAS catalog 1001148
MESH D011081
SNOMED CT 72275000

Key figures

Sex All Female Male
Number of individuals 1520 827 693
Unadjusted prevalence (%) 1.15 1.1 1.21
Mean age at first event (years) 37.86 39.56 35.82
Median number of events / individual 1 1 1

Clinical metrics

Sex All Female Male
Recurrence within 6 months (%) 19.08 18.86 19.34
Case fatality at 5-years (%) 0.79 0.73 0.87

Associations