Other disorders involving the immune mechanism, not elsewhere classified
Description
Mastocytosis: A clonal myeloproliferative neoplasm characterized by the proliferation and accumulation of neoplastic mast cells in one or multiple organs or organ systems. It is a heterogeneous group of neoplasms, ranging from cutaneous proliferations which may regress spontaneously, to aggressive neoplasms associated with organ failure and short survival.
Data source
| FinnGen phenocode | D3_IMMUNEMECHANISMOTHER |
| Hospital Discharge registry | ICD-10: D89 |
| Cause of Death registry | ICD-10: D89 |
| Include | D3_POLYCLOHYPERGAMMA, D3_CRYOGLOBU, D3_HYPERGAMMAGLONAS, D3_IMMUNEMECHANISMNAS |
| Level in the ICD-hierarchy | 3 |
| First defined in version | DF2 |
Key figures
| Sex | All | Female | Male |
| Number of individuals | 207 | 76 | 131 |
| Unadjusted prevalence (%) | 0.16 | 0.1 | 0.23 |
| Mean age at first event (years) | 50.56 | 46.27 | 53.05 |
| Median number of events / individual | 5 | 3 | 6 |
Clinical metrics
| Sex | All | Female | Male |
| Recurrence within 6 months (%) | 61.35 | 53.95 | 65.65 |
| Case fatality at 5-years (%) | 6.28 | 1.32 | 9.16 |