Disorders of eyelid, lacrimal system and orbit

Description

orbital plasma cell granuloma: A nonspecific tumor-like inflammatory lesion in the ORBIT of the eye. It is usually composed of mature LYMPHOCYTES; PLASMA CELLS; MACROPHAGES; LEUKOCYTES with varying degrees of FIBROSIS. Orbital pseudotumors are often associated with inflammation of the extraocular muscles (ORBITAL MYOSITIS) or inflammation of the lacrimal glands (DACRYOADENITIS).

Data source
FinnGen phenocode H7_LIDLACRIMALORBIT
Include H7_HORDEOLUM, H7_CHALAZION, H7_EYELIDINFLAMMATION, H7_EYELIDDIS, H7_LACRIMALSYSTEM, H7_ORBIT
Level in the ICD-hierarchy 2
First defined in version DF2
Ontology
DOID 9369
GWAS catalog 1001077

Key figures

Sex All Female Male
Number of individuals 9106 6029 3077
Unadjusted prevalence (%) 6.87 8.02 5.36
Mean age at first event (years) 56.98 56.1 58.71
Median number of events / individual 1 1 1

Clinical metrics

Sex All Female Male
Recurrence within 6 months (%) 27.95 27.98 27.88
Case fatality at 5-years (%) 3.18 2.39 4.74

Associations