Cerebrovascular diseases

Description

intracranial embolism: Blocking of a blood vessel in the skull by an embolus which can be a blood clot (thrombus) or other undissolved material in the blood stream. Most emboli are of cardiac origin and are associated with heart diseases. Other non-cardiac sources of emboli are usually associated with vascular diseases.

Data source
FinnGen phenocode I9_CEREBVASC
Include I9_SAH, I9_ICH, I9_OTHINTRACRA, I9_STR_EXH, I9_STENOSIS, I9_DISCER, I9_ANEURYSM, I9_ANEUR, I9_CERATHER, I9_PROGVASC, I9_HYPERTENC, I9_MOYAMO, I9_THROMBICV, I9_CEREBRART, I9_CEREBDOTH, I9_CEREBAMY, I9_SEQULAE
Level in the ICD-hierarchy 2
First defined in version DF2
Ontology
DOID 4372
GWAS catalog 1000991
MESH D020766
SNOMED CT 75543006

Key figures

Sex All Female Male
Number of individuals 9523 4430 5093
Unadjusted prevalence (%) 7.18 5.9 8.87
Mean age at first event (years) 64.32 64.77 63.92
Median number of events / individual 2 2 2

Clinical metrics

Sex All Female Male
Recurrence within 6 months (%) 42.53 41.08 43.79
Case fatality at 5-years (%) 17.46 17.09 17.79

Associations