Hypertensive heart and/or renal disease


nephrosclerosis: Hardening of the walls of the small arteries and arterioles (small arteries that convey blood from arteries to the even smaller capillaries) of the kidney. This condition is caused by hypertension (high blood pressure)

Data source
FinnGen phenocode I9_HYPTENSHR
Hospital Discharge registry ICD-10: I13/I11/I12, ICD-9: 4039A/4040A/4029B/4029A, ICD-8: 40299|40399|40499
Cause of Death registry ICD-10: I13/I11/I12, ICD-9: 4029B/4029A/4039A/4040A, ICD-8: 40299|40399|40499
Level in the ICD-hierarchy 3
First defined in version DF2
DOID 11664
GWAS catalog 1000041
MESH D009400
SNOMED CT 32916005

Key figures

Sex All Female Male
Number of individuals 3053 1400 1653
Unadjusted prevalence (%) 2.3 1.86 2.88
Mean age at first event (years) 65.26 67.95 62.98
Median number of events / individual 1 1 1

Clinical metrics

Sex All Female Male
Recurrence within 6 months (%) 22.57 21.07 23.84
Case fatality at 5-years (%) 18.54 19.5 17.73