Other peripheral vascular diseases

Description

thromboangiitis obliterans: Buerger disease, also known as thromboangiitis obliterans (TAO), is a rare inflammatory non-necrotizing vascular disease affecting the small- and medium-sized arteries and veins of the upper and lower extremities characterized by endarteritis and vaso-occlusion due to occlusive thrombus development. The development and progression of the disease is consistently associated with exposure to tobacco.

Data source
FinnGen phenocode I9_OTHPER
Hospital Discharge registry ICD-10: I73, ICD-9: 443, ICD-8: 443
Cause of Death registry ICD-10: I73, ICD-9: 443, ICD-8: 443
Include I9_THROMBANG
Level in the ICD-hierarchy 3
First defined in version DF2
Ontology
DOID 12918
GWAS catalog 1001211
MESH D013919
SNOMED CT 52403007

Key figures

Sex All Female Male
Number of individuals 621 387 234
Unadjusted prevalence (%) 0.47 0.52 0.41
Mean age at first event (years) 50.31 47.48 55.0
Median number of events / individual 1 1 1

Clinical metrics

Sex All Female Male
Recurrence within 6 months (%) 26.25 26.1 26.5
Case fatality at 5-years (%) 4.03 2.33 6.84

Associations