Diseases of liver
Description
primary biliary cirrhosis: Primary biliary cholangitis (PBC) is a chronic and slowly progressive cholestatic liver disease of autoimmune etiology characterized by injury of the intrahepatic bile ducts that may eventually lead to liver failure.
Data source
| FinnGen phenocode | K11_LIVER |
| Include | K11_ALCOLIV, K11_TOXLIV, K11_HEPFAIL, K11_CHRONHEP, K11_FIBROCHIRLIV, K11_OTHINFLIV, K11_DISLIVOTH, K11_LIVDISINOTH |
| Level in the ICD-hierarchy | 2 |
| First defined in version | DF2 |
Key figures
| Sex | All | Female | Male |
| Number of individuals | 2965 | 1457 | 1508 |
| Unadjusted prevalence (%) | 2.24 | 1.94 | 2.63 |
| Mean age at first event (years) | 52.6 | 52.52 | 52.67 |
| Median number of events / individual | 1 | 1 | 1 |
Clinical metrics
| Sex | All | Female | Male |
| Recurrence within 6 months (%) | 36.86 | 40.7 | 33.16 |
| Case fatality at 5-years (%) | 15.45 | 8.72 | 21.95 |