Polyarteritis nodosa and related conditions
Description
Polyarteritis Nodosa: ['A necrotizing vasculitis that affects medium-sized arteries, it is usually idiopathic, and may be triggered by viral infections (Hepatitis B, also others). A multisystem disease, it most commonly affects skin (nodules, livedo reticularis) and peripheral nerves; higher morbidity is associated with gastrointestinal, central nervous system, cardiac, and/or other organ involvement. Anti-neutrophil cytoplasmic antibodies (ANCA) are typically negative. [ NCI ]']
Data source
| FinnGen phenocode | M13_POLYARTERETAL |
| Hospital Discharge registry | ICD-10: M30 |
| Cause of Death registry | ICD-10: M30 |
| Include | M13_POLNODOSA, M13_CHURGSTRAUSS, M13_JUVEPOLYNOD, M13_KAWASAKI, M13_POYARTOTH |
| Level in the ICD-hierarchy | 3 |
| First defined in version | DF2 |
Key figures
| Sex | All | Female | Male |
| Number of individuals | 93 | 60 | 33 |
| Unadjusted prevalence (%) | 0.07 | 0.08 | 0.06 |
| Mean age at first event (years) | 53.18 | 52.15 | 55.04 |
| Median number of events / individual | 1 | 1 | 1 |
Clinical metrics
| Sex | All | Female | Male |
| Recurrence within 6 months (%) | 38.71 | 41.67 | 33.33 |
| Case fatality at 5-years (%) | 11.83 | 8.33 | 18.18 |