Diseases of arteries, arterioles and capillaries
Description
thromboangiitis obliterans: Buerger disease, also known as thromboangiitis obliterans (TAO), is a rare inflammatory non-necrotizing vascular disease affecting the small- and medium-sized arteries and veins of the upper and lower extremities characterized by endarteritis and vaso-occlusion due to occlusive thrombus development. The development and progression of the disease is consistently associated with exposure to tobacco.
Data source
| FinnGen phenocode | I9_DOAAC |
| Include | I9_ATHSCLE, I9_AORTDIS, I9_AORTANEUR, I9_OTHANEUR, I9_OTHPER, I9_ARTEMBTHR, I9_ARTOTH, I9_PAD, I9_VASCINT |
| Level in the ICD-hierarchy | 2 |
| First defined in version | DF2 |
Key figures
| Sex | All | Female | Male |
| Number of individuals | 7017 | 2787 | 4230 |
| Unadjusted prevalence (%) | 5.29 | 3.71 | 7.37 |
| Mean age at first event (years) | 63.3 | 62.23 | 64.0 |
| Median number of events / individual | 2 | 2 | 2 |
Clinical metrics
| Sex | All | Female | Male |
| Recurrence within 6 months (%) | 50.04 | 43.81 | 54.14 |
| Case fatality at 5-years (%) | 15.22 | 14.57 | 15.65 |