Other disorders of skin and subcutaneous tissue

Description

skin atrophy: The structural changes and the signs and symptoms of chronologically aged skinand those of corticosteroid induced chronicatrophyof theskinare partially very similar.Thinningof epidermis and laxity as well as dryness, purpura and echymoses occur in both conditions.

Data source
FinnGen phenocode L12_OTHERSKINSUBCUTIS
Include L12_VITILIGO, L12_OTHPIGMENTATION, L12_SEBORRKERAT, L12_ACANTHNIGRICANS, L12_CORNSANDCALLOS, L12_EPIDERMALTHICKOTH, L12_ACQICTHY, L12_ACQKERAT, L12_KERATPUNCTATA, L12_XEROSCUT, L12_EPIDERMTHICKNAS, L12_KERATODERMAINOTH, L12_TRANSEPIDERMELIMINATION, L12_PYODERMAGANGRENOSUM, L12_DECUBITANSULCERANDPRESSURE, L12_ATROPHICSKIN, L12_LICHENSCLERATROPH, L12_ANETODERMA, L12_ATROPODERMAPASINI, L12_ACRODERMATITIS, L12_SCARCONDITIONS, L12_STRIAEATROPHICAE, L12_ATROPHICSKINNAS, L12_HYPERTROPHICSKIN, L12_GRANULOMATOUSSKIN, L12_LUPUS, L12_LOCALDCONNECTISSUEOTH, L12_VASCULITISSKIN, L12_ULCERLOWLIMB, L12_OTHERDISSKINANDSUBCUTIS, L12_SKININOTH
Level in the ICD-hierarchy 2
First defined in version DF2
Ontology
DOID 2733
GWAS catalog 1000766
SNOMED CT 400190005

Key figures

Sex All Female Male
Number of individuals 6548 4050 2498
Unadjusted prevalence (%) 4.94 5.39 4.35
Mean age at first event (years) 56.12 55.25 57.54
Median number of events / individual 1 1 1

Clinical metrics

Sex All Female Male
Recurrence within 6 months (%) 31.9 32.67 30.66
Case fatality at 5-years (%) 7.01 4.77 10.65

Associations