Other necrotizing vasculopathies

Description

Takayasu arteritis: Takayasu arteritis (TAK) is a rare inflammatory large-vessel vasculitis primarily affecting the aorta and its major branches, but also other large vessels, causing stenosis, occlusion, or aneurysm.

Data source
FinnGen phenocode M13_NECROVASC
Hospital Discharge registry ICD-10: M31
Cause of Death registry ICD-10: M31
Include M13_HYPERANG, M13_HTROMBMICROANG, M13_MIDGRANULOMA, M13_WEGENER, M13_TAKAYASU, M13_GIANTCELL, M13_MICROPOLYANG, M13_NECROVASCNAS
Level in the ICD-hierarchy 3
First defined in version DF2
Ontology
DOID 2508
GWAS catalog 1001857
MESH D013625
SNOMED CT 239937004

Key figures

Sex All Female Male
Number of individuals 511 322 189
Unadjusted prevalence (%) 0.39 0.43 0.33
Mean age at first event (years) 60.35 60.54 60.03
Median number of events / individual 3 3 5

Clinical metrics

Sex All Female Male
Recurrence within 6 months (%) 59.1 57.14 62.43
Case fatality at 5-years (%) 9.39 7.45 12.7

Associations